Sodium Channels Grit, Determination, and Persistence
نویسنده
چکیده
Persistent sodium channel activity modulates neuronal gain in a neurotransmitter-dependent fashion. Previous studies have suggested that persistent and spike-related sodium channel activities are mediated by separate species. In this issue of Neuron, Taddese and Bean (2002) show that a single channel population is sufficient to explain both gating behaviors. A simple allosteric model is provided that can explain the results.
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عنوان ژورنال:
- Neuron
دوره 33 شماره
صفحات -
تاریخ انتشار 2002